个人简介
张学楷，博士，讲师，硕士生导师。2017年于南开大学获有机化学博士学位，师从陈弓教授；2018年至2020年在美国宾州州立大学/霍华德·休斯医学研究所从事博士后研究，合作导师为美国科学院院士Squire J. Booker；2021年9月起任山东科技大学讲师。主持国家自然科学基金青年项目、国家博士后面上项目、山东省自然科学基金青年项目等多项课题，相关研究成果发表于Nature Chemistry、JACS、PNAS等国际高水平期刊，获授权发明专利1项。
研究方向
氨基酸与多肽的化学修饰；光电化学（PEC）有机合成；药物合成工艺研究
承担项目
（1）国家自然科学基金青年项目，30万，主持。
（2）国家博士后面上项目，8万，主持。
（3）山东省自然科学基金青年项目，15万，主持。
（4）山东科技大学“菁英计划”人才引进项目，30万，主持。
（5）横向课题2-氨基-4-氟吡啶合成工艺研究，20万，主持。
个人成果
1. Jingran Xiao#, Xinmou Wang#, Linzheng Ma#, Chenxu Wang, Lihua Wei, Fangyu Gong, Chaoxu Wang, Chengyi Liang, Gong Chen*, Xuekai Zhang*. Copper-Catalyzed Late-Stage C(sp3)–H Amination of N-Terminal Glycine Peptides with Secondary Alkylamines. Journal American Chemical Society, 2026, 148, 40213-40225.
2. Nicholas J. York*, Xuekai Zhang, Squire J. Booker*. Isolation and in vitro characterization of BchE, the cobalamin-dependent anaerobic magnesium protoporphyrin IX monomethylester cyclase. Proceedings of the National Academy of Sciences U.S.A., 2026, 123, e2615158123.
3. Xuekai Zhang, Xueli Sun, Xin Jia, Yuqian Wang, Fengxiang Yu, Guohao Pang, Xinning Shi, Jun Zhong, Jingran Xiao*. Bypassing surface state limitations on modified hematite photoanodes via two-electron thiol coupling for stable photoelectrochemical disulfide synthesis. Chemical Engineering Journal, 2026, 547, 181370.
4. Jialin Sun, Binbin Wang, Zunyan Nie, Xin Jia, Chunxiao Li, Mingjun Li, Yingchun Zhao, Xuekai Zhang*, Bo Wang*, Jingran Xiao*. Selective Oxidation of Alcohol to Valuable Aldehydes Using Water as a Promoter in a Photoelectrochemical Cell. Langumir, 2024, 40, 13265-13275.
5. Jingran Xiao*, Xin Jia, Borui Du, Ziqi Zhong, Chunxiao Li, Jialin Sun, Zunyan Nie, Xuekai Zhang*, Bo Wang*. Balancing charge recombination and hole transfer rates in hematite photoanodes by modulating the Co2+/Fe3+ sites in the OER cocatalyst. Journal of Colloid and Interface Science, 2024, 654, 915-924.
6. Jingran Xiao*, Chunxiao Li, Xin Jia, Jialin Sun, Feiler Liubov, Chengyi Liang, Xuekai Zhang*, Bo Wang*. Reaction kinetics of photoelectrochemical water and 5-hydroxymethylfurfural oxidation on rutile nanorod photoanode with Ge doping and core/shell structure. Electrochimica Acta, 2024, 475, 143643-143653.
7. Jinghui Zhang#, Huixin Xu#, Baishi Wang#, Xuekai Zhang#, Lei Fu, Yannan Li, Guanzhao Wu, Zitong Zhao, Lu Liu, Ting Yang, Zheyu Zhang, Jinbo Yang, Tao Jiang, Peiju Qiu*, Rilei Yu*. In silico design of anti-tumor mini-protein targeting MDM2, Chinese Chemical Letters, 2023, 34, 107871-107873.
8. Xuekai Zhang, Gang Lu, Meng Sun, Madhu Mahankali, Yanfei Ma, Mingming Zhang, Wangde Hua, Yuting Hu, Qingbing Wang, Jinghuo Chen, Gang He*, Xiangbing Qi*, Weijun Shen*, Peng Liu* and Gong Chen*. A General Strategy for Synthesis of Cyclophane-Braced Peptide Macrocycles via Palladium-Catalyzed Intramolecular sp3 C–H Arylation. Nature Chemistry, 2018, 10, 540-548.
9. 陈弓，张学楷。一种新型大环环肽化合物的合成方法。专利号（授权）：CN106995483B.
招生专业：化学（学硕）；生物与医药（专硕）
邮 箱：xuekaizhang@sdust.edu.cn
